http://www.imng.com Elsevier Global Medical News Group has provided physician specialists with authoritative coverage of medical meetings, breaking medical news and analysis, clinical trial results, updates on drug prescribing, pertinent summaries of clinical guidelines, and perspective and opinion from medicine thought leaders. Copyright 2012 Elsevier Global Medical News. All rights reserved. en-us Sat, 19 May 2012 07:00:04 GMT InfoDesk http://media.ny.idsk.com/multimedia/logos/rsslogo_imng.gif http://www.imng.com http://infoviewer.biz/infodisplay/story/imn051820121644542418.html?APP=7&CU=imn5804 All adults born between 1945 and 1965 should have a one-time blood test for hepatitis C, according to recommendations proposed by the Centers for Disease Control and Prevention. BY ELIZABETH MECHCATIE Fri, 18 May 2012 20:44:54 GMT imn051820121644542418 http://infoviewer.biz/infodisplay/story/imn051820121620552416.html?APP=7&CU=imn5804 BOSTON (EGMN) – Many infants with a fever of unknown origin can be safely discharged from the hospital sooner than the routinely recommended 48 hours, a study has shown. BY MICHELE G. SULLIVAN Fri, 18 May 2012 20:20:55 GMT imn051820121620552416 http://infoviewer.biz/infodisplay/story/imn051820121553562413.html?APP=7&CU=imn5804 RALEIGH, N.C. (EGMN) – Once-daily application of an emollient from birth through age 6 months has shown considerable promise as a means of preventing atopic dermatitis, according to the Barrier Enhancement for Eczema Prevention study. BY BRUCE JANCIN Fri, 18 May 2012 19:53:56 GMT imn051820121553562413 http://infoviewer.biz/infodisplay/story/imn051820121531552411.html?APP=7&CU=imn5804 SAN DIEGO (EGMN) – Oral tranexamic acid tablets at a dose of up to 3.9 g/day reduced blood loss by a mean of at least 60-65 mL per menstrual period in women aged 30 or older with heavy menstrual bleeding, a pooled analysis of two pivotal trials found. BY SHERRY BOSCHERT Fri, 18 May 2012 19:31:55 GMT imn051820121531552411 http://infoviewer.biz/infodisplay/story/imn051820121516552407.html?APP=7&CU=imn5804 Obese children seem to have gotten fatter around the middle over time, and that development may account in part for an observed increase in suspected nonalcoholic fatty liver disease among adolescents. BY DIANA MAHONEY Fri, 18 May 2012 19:16:55 GMT imn051820121516552407 http://infoviewer.biz/infodisplay/story/imn051820121444532404.html?APP=7&CU=imn5804 SAN DIEGO (EGMN) – Women expelled 54% of intrauterine devices placed immediately after giving birth, compared with a 6% expulsion rate after conventional placement at 6 weeks post partum or later, a study of an indigent population found. BY SHERRY BOSCHERT Fri, 18 May 2012 18:44:53 GMT imn051820121444532404 http://infoviewer.biz/infodisplay/story/imn051820121429522402.html?APP=7&CU=imn5804 NEW ORLEANS (EGMN) – The incidence of hospitalizations for status epilepticus rose nearly fourfold during 1980-2009, according to researchers who analyzed the National Center for Health Statistics’ National Hospital Database Survey. BY JEFF EVANS Fri, 18 May 2012 18:29:52 GMT imn051820121429522402 http://infoviewer.biz/infodisplay/story/imn051820121414572401.html?APP=7&CU=imn5804 BARCELONA (EGMN) – It is a long held and substantiated belief that osteoarthritis is a biomechanical disease, but evidence is accumulating to support an inflammatory cause. As testament to the strength of both possible causes of the disease, the vote after the World Congress on Osteoarthritis debate, titled “Is OA a mechanical disease or an inflammatory disease?” resulted in a swing from approximately 70/30 in favor of a biomechanical explanation, to 50/50. BY BECKY MCCALL Fri, 18 May 2012 18:14:57 GMT imn051820121414572401 http://infoviewer.biz/infodisplay/story/imn051820121347552395.html?APP=7&CU=imn5804 BOSTON (EGMN) – Tweaking implantable cardioverter defibrillator settings to lengthen the detection window is safe and significantly reduces inappropriate antitachycardia pacing and shocks, an investigator said at the annual meeting of the Heart Rhythm Society. BY NEIL OSTERWEIL Fri, 18 May 2012 17:47:55 GMT imn051820121347552395 http://infoviewer.biz/infodisplay/story/imn051820121234512392.html?APP=7&CU=imn5804 SAN DIEGO (EGMN) – As birth weight increases, progression in labor was slower both in successful trial of labor patients and in patients who ultimately had cesarean deliveries. BY DOUG BRUNK Fri, 18 May 2012 16:34:51 GMT imn051820121234512392 http://infoviewer.biz/infodisplay/story/imn051820121158542389.html?APP=7&CU=imn5804 NEW ORLEANS (EGMN) – How long does it take before the cumulative effect of repeated blows to the head result in significant cognitive changes? Preliminary results from a longitudinal study of boxers and mixed martial arts fighters suggest that it takes maybe a dozen years – but that anatomical changes begin showing up in half that time. BY ALICIA AULT Fri, 18 May 2012 15:58:54 GMT imn051820121158542389 http://infoviewer.biz/infodisplay/story/imn051820121151302386.html?APP=7&CU=imn5804 SAN FRANCISCO (EGMN) – Data from the Interagency Registry for Mechanically Assisted Circulatory Support has identified significant risk factors for death following implantation of left ventricular assist devices as destination therapy. The findings will allow better targeting of patients who can expect 1- and 2-year survival rates on left ventricular assist devices (LVADs) that approach those seen with heart transplantation, according to Dr. James K. Kirklin. BY DAMIAN MCNAMARA Fri, 18 May 2012 15:51:30 GMT imn051820121151302386 http://infoviewer.biz/infodisplay/story/imn051820121105272381.html?APP=7&CU=imn5804 BOSTON (EGMN) – Preventive antifungal therapy and changes in broad-spectrum antibiotic use were associated with a significant decrease in the incidence of invasive candidiasis in neonatal intensive care units. BY MICHELE G. SULLIVAN Fri, 18 May 2012 15:05:27 GMT imn051820121105272381 http://infoviewer.biz/infodisplay/story/imn051820121057572380.html?APP=7&CU=imn5804 Digital ulcers are a frequent manifestation of systemic sclerosis, affecting approximately half of all patients with the multisystem connective tissue disorder. Often persistent and recurring, these ischemic wounds tend to be slow-healing and difficult to manage. In addition to pain and disability, severe complications such as tissue loss, infection, gangrene, autoamputation, and septicemia can exacerbate the clinical burden by an order of magnitude, according to Christopher Denton, Ph.D., director of the Center for Rheumatology at University College London. BY DIANA MAHONEY Fri, 18 May 2012 14:57:57 GMT imn051820121057572380 http://infoviewer.biz/infodisplay/story/imn051720121719572377.html?APP=7&CU=imn5804 Just as Sanofi-Aventis loses its exclusivity for its blockbuster drug Plavix (clopidogrel) this month, several generic formulations of the antiplatelet agent have been approved, the Food and Drug Administration announced on May 17. BY ELIZABETH MECHCATIE Thu, 17 May 2012 21:19:57 GMT imn051720121719572377 http://infoviewer.biz/infodisplay/story/imn051720121639512374.html?APP=7&CU=imn5804 NEW ORLEANS (EGMN) – Women with epilepsy appear to have a significantly greater number of unintended pregnancies than does the general population and cite a wide variety of reasons for discontinuing different contraceptive methods, according to preliminary results from the Epilepsy Birth Control Registry. BY JEFF EVANS Thu, 17 May 2012 20:39:51 GMT imn051720121639512374 http://infoviewer.biz/infodisplay/story/imn051720121620592372.html?APP=7&CU=imn5804 Combining the BRAF inhibitor dabrafenib with the MEK inhibitor trametinib dramatically delays metastatic melanoma progression without the skin toxicities associated with vemurafenib therapy. BY PATRICE WENDLING Thu, 17 May 2012 20:21:05 GMT imn051720121620592372 http://infoviewer.biz/infodisplay/story/imn051720121548542369.html?APP=7&CU=imn5804 The recently approved cancer drug crizotinib draws strong responses in children whose cancers have mutations in the gene targeted by the drug, according to early data from a phase I dose-escalating study. BY KERRI WACHTER Thu, 17 May 2012 19:48:54 GMT imn051720121548542369 http://infoviewer.biz/infodisplay/story/imn051720121503572365.html?APP=7&CU=imn5804 SAN DIEGO (EGMN) – Women with vulvodynia who received one counseling session with a licensed social worker after their diagnosis reported increased knowledge about their condition and less impact of vulvar symptoms on their lives, compared with women who did not receive the session, results from a pilot study showed. BY DOUG BRUNK Thu, 17 May 2012 19:03:57 GMT imn051720121503572365 http://infoviewer.biz/infodisplay/story/imn051720121447532363.html?APP=7&CU=imn5804 SAN DIEGO (EGMN) – Something as simple as a stamp in a patient’s chart to remind medical providers about vaccinating against human papillomavirus nearly quintupled the percentage of eligible patients being vaccinated in one outpatient office, according to a poster presented at the annual meeting of the American College of Obstetricians and Gynecologists. BY SHERRY BOSCHERT Thu, 17 May 2012 18:47:53 GMT imn051720121447532363